While holding the tube in an upright position, remove the cap from the tube. Just to be on the safe side, I asked for a blood work and a full body exam and everything came back normal, except hes anemic from the fleas biting him. Advantage flea treatment is waterproof. This is temporary and does not affect the safety and effectiveness of the product. age of your dog and use the medication accordingly. You should also take him to the vet at the earliest, for treatment. important to apply the medication between your pet’s shoulder blades to Side Effects of Advantage Flea Treatment. Do not allow the dog to lick any of the application sites for. Fleas may then be removed from the coat by picking or combing. The dog should be standing for application. Although Advantage flea treatment is considered safe, some dogs might body weight. For consumer questions call 1-800-255-6826. Increased RBC, hemoglobin, activated partial thromboplastin, and direct bilirubin were observed in the treated group. For a copy of the Material Safety Data Sheet (MSDS) or to report adverse reactions call Bayer Veterinary Services at 1-800-422-9874. Pyrethrin and pyrethroid are insecticides typically used for treating flea and tick infestations. Occasionally hair loss also occurs. Avoid contact with skin. For dogs weighing 20 lbs. dgsgirl Do not dispense dose applicator tubes without complete safety and administration information. Another dog exhibited abnormal neurological signs (circling, ataxia, generalized muscle tremors, and dilated pupils with a slow pupillary light response) starting at 4 hours post-dosing through 18 hours post-dosing. (See CONTRAINDICATIONS.). As specified in the following table, administer the entire contents of the Advantage Multi® for Dogs tube that correctly corresponds with the body weight of the dog. Advantage Treatment Spray for Dogs Caution … In addition, The Material Safety Data Sheet (MSDS) provides additional occupational safety information. Your pet might also appear non-responsive, 3. In households with multiple pets, keep each treated dog separated from other treated dogs and other pets for 30 minutes after application to prevent licking the application sites. Thanks to its ability to improve blood circulation, it impacts blood vessels and in turn, could cause unwanted bleeding. Such The following adverse events were reported in humans: eye irritation, allergic reactions, skin irritation, skin tingling, sore throat, and chemical odor. Advantage Multi for Dogs is also indicated for the treatment and control of the following intestinal parasites: Do not administer this product orally. Enter code VET30 to receive 30% off your first Autoship eligible purchase of any single vet-authorized diet dog or cat food. Method: OECD TG 474 Reproductive toxicity: Propan-2-ol Result: Animal testing did not show any effects … Most Common Side Effects of Frontline for Dogs. Dermal Safety Study in Ivermectin-Sensitive Collies:Advantage Multi for Dogs was administered topically at 3 and 5X the recommended dose every 28 days for 3 treatments to Collies which had been pre-screened for avermectin sensitivity. or less, place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at one spot between the shoulder blades. Sensitivities may occur after using any pesticide product on pets. Heartworm Prevention: For prevention of heartworm disease, Advantage Multi for Dogs should be administered at one-month intervals. It is formulated for dogs and puppies over 12 weeks. The signs in this dog may have been related to peak serum levels of moxidectin, which vary between dogs, and occur between 1 and 21 days after application of Advantage Multi for Dogs. If your pet exhibits any symptoms of an adverse side effect to If contact with skin or clothing occurs, take off contaminated clothing. Use Advantage flea treatment products to help kill fleas on your dog. Without treatment, this dog was neurologically normal at 24 hours and had a normal appetite by 48 hours post-dosing. At the discretion of the veterinarian, infected dogs should be treated with an adulticide to remove adult heartworms. Ingestion of this product by dogs may cause serious. Bayer Advantage II Topical Flea Treatment for Dogs. Advantage flea control is a monthly treatment that should be applied However, shampooing as often as once weekly may reduce the effectiveness of the product against fleas. Safety Study in Heartworm-Positive Dogs: Advantage Multifor Dogs was administered topically at 1 and 5X the recommended dose every 14 days for 3 treatments to dogs with adult heartworm infections and circulating microfilariae. Causes eye irritation. Dermal Dose Tolerance Study: Advantage Multi for Dogs was administered topically to 8-month-old Beagle dogs at 10X the recommended dose once. Side effects of fipronil and when to report them. Do not induce vomiting unless told to do so by the poison control center or physician. more severe and may include coma and death.2. 08891454 6 x 0.4 mL tubes, 08891462 6 x 1.0 mL tubes, 08891470 6 x 2.5 mL tubes, 08891489 6 x 4.0 mL tubes, 80560290 6 x 5.0 mL tubes. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin based on body weight. At 40% of the minimum recommended topical dose, 4 of the dogs experienced neurological signs indicative of avermectin toxicity including depression, ataxia, mydriasis, salivation, muscle fasciculation, and coma, and were euthanized. manufactured by Bayer and is the brand name for imidacloprid, an Some pet owners have reported numbness after having contact with Advantage. (See, Ensure that dogs cannot lick the product from, Separate treated dogs from one another and from. Spray Flea Treatments for Dogs: Cheap and very easy to use, dog flea spray treatments are often the first-choice for many owners. Advantage Flea & Tick Treatment Spray for Dogs designed to aid in the control of flea bite dermatitis, this EPA-regulated spray works to kill and repel fleas, flea eggs, flea larvae, ticks and lice on contact. Advantage Treatment Spray for Dogs Version 2.0 Revision Date 10/22/2013 Page 7 of 10 Genotoxicity in vivo: Propan-2-ol Micronucleus test, mouse Result: No indication of clastogenic effects. pour large amounts of warm water over him to wash out the medication. Box 390 Shawnee Mission, Kansas 66201 U.S.A. Harmful if swallowed. Side Effects Some people have reported side effects from having contact with Advantage. Side Effects Although I know side effects are always possible with any flea treatment. application sites on themselves or other treated dogs, and. Federal (U.S.A.) Law restricts this drug to use by or on the order of a licensed veterinarian. I have had problems with other flea medications. No clinical abnormalities were observed. Once-a-month topical solution for the prevention of heartworm disease, kills adult fleas, is indicated for the treatment of flea infestations, as well as the treatment and control of intestinal parasite infections in dogs and puppies that are at least 7 weeks of age and that weigh at least 3 lbs. undisclosed ingredients might be unsafe for use on your pet and the When replacing another heartworm preventative product in a heartworm prevention program, the first treatment with Advantage Multi for Dogs should be given within one month of the last dose of the former medication. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Advantage flea treatment is made by the company Bayer, and its active ingredient is imidacloprid. of the fleas. Prior to administration of Advantage Multi for Dogs, dogs should be tested for existing heartworm infection. Advantage Treatment Sprays - Advantage Flea & Tick Treatment Spray for Dogs designed to aid in the control of flea bite dermatitis, this EPA-regulated spray works to kill and repel fleas, flea eggs, flea larvae, ticks and lice on contact. It’s one of the safest and most effective treatments (See WARNINGS.). If swallowed, call poison control center or physician immediately for treatment advice. Discount taken off highest priced qualifying vet-authorized diet … age of 7 months. (See WARNINGS.). Canine Flea Control with Advantage for Dogs, Treating Flea Bites on Cats with Adulticides, It’s easily available in local stores and pharmacies, It eradicates fleas on your pet within 12 hours of application and kills the larvae as well. Although Advantage flea treatment is considered safe, some dogs might develop an adverse reaction to this treatment. Owners reported the following signs in their dogs after application of Advantage Multifor Dogs: pruritus, flaky/greasy residue at the treatment site, medicinal odor, lethargy, inappetence, and hyperactivity. Imidacloprid is a chloronicotinyl nitroguanidine insecticide. Store at temperatures between 4°C (39°F) and 25°C (77°F), avoiding excess heat or cold. For dogs, imidacloprid is sold under the brand name of Advantage and is used as a topical flea control once monthly. Do not get in eyes or on clothing. Advantage Multi for Dogs is indicated for the prevention of heartworm disease caused by Dirofilaria immitis.Advantage Multi for Dogs kills adult fleas and is indicated for the treatment of flea infestations (Ctenocephalides felis). Another active ingredient is Pyrethrins, which is a pest-killing insecticide that works on contact. pet within 5 minutes of application and flea larvae are killed with 20 Do not apply an amount of solution at any one location that could run off the side of the dog. insecticide. Shampooing 90 minutes after treatment does not reduce the effectiveness of Advantage Multi for Dogs in the prevention of heartworm disease. minimize the risk of your pet licking the medication off and It’s effective in paralyzing and subsequently killing Laboratory Effectiveness Studies: One dog in a laboratory effectiveness study experienced weakness, depression, and unsteadiness between 6 and 9 days after application with Advantage Multi for Dogs. Caution with Spot-On Products FRIDAY, Sept. 21, 2018 (HealthDay News) -- Flea medicines protect your pet, but some animals can have serious side effects from products containing isoxazoline, U.S. health officials warn. Advantage Multi for Dogs was used safely in dogs concomitantly receiving ACE inhibitors, anticonvulsants, antihistamines, antimicrobials, chondroprotectants, corticosteroids, immunotherapeutics, MAO inhibitors, NSAIDs, ophthalmic medications, sympathomimetics, synthetic estrogens, thyroid hormones, and urinary acidifiers. Side effects to a dog flea control product include irritation or redness where a topical product was placed, hair loss, vomiting, lethargy, and diarrhea. exhibit adverse reactions to this medication. pet’s body. The active ingredient present in Advantage acts on the nervous system Side effects of arnica for dogs ⚠️ If your dog has ingested the topical form of arnica, alert Animal Poison Control immediately: (888) 426-4435 Arnica can increase bleeding. of application. Since the medication is Observations at the application sites included damp, stiff or greasy hair, the appearance of a white deposit on the hair, and mild erythema, which resolved without treatment within 2 to 48 hours. Dosage Form: FOR ANIMAL USE ONLY. the treatment is not used as advised by the manufacturers. Oral Safety Study in Beagles: Advantage Multi for Dogs was administered once orally at the recommended topical dose to 12 dogs. If signs continue, consult a veterinarian immediately. You should Since the medication is applied to your pet’s skin, it can be absorbed by the skin and enter the pet’s body. Wash skin immediately with plenty of soap and water. One dog showed signs of treatment site irritation after application. Flea Treatment: For the treatment of flea infestations, Advantage Multi for Dogs should be administered at one-month intervals. your pet, their life cycle is broken in multiple stages. These effects are temporary and will not affect safety or effectiveness of the product. Fleas may then be removed from the coat by picking or combing. the application site and lethargy. Bayer HealthCare LLC Potential side effects of Advantage MULTI for Dogs: Hair may become damp, matted, oily, or stiff after application; skin may appear pink or have a slight powdery residue; medicinal odor. Advantage Multi for Dogs may be administered year-round or at a minimum should start one month before the first expected exposure to mosquitoes and should continue at monthly intervals until one month after the last exposure to mosquitoes. minutes of application. Hypersensitivity reactions were not seen in the 5X treatment group. difficulty in breathing. A great complement to a complete flea control program, this easy-to-use, leave-on spray can be applied directly to your pup, as well as carpets, upholstery, bedding, floor gaps and more. Advantage flea treatment, you should wash him with a mild shampoo and Copyright © document.write(new Date().getFullYear()) MH Sub I, LLC dba Internet Brands. Is Advantage Flea Treatment Dogs Safe for Long Term Use? For best results, all dogs should be treated with a similar flea control product such as Advantage® Treatment Spray for Dogs to prevent re-infestation. I haven't found anything that is nearly as effective as Advantage Flea Control for Dogs. Put some spray on the finger and gently rub around eyes, nose, and mouth area. At 5X, one dog was observed vomiting three hours after the second treatment. Do not use this product (containing 2.5% moxidectin) on cats. While the number of circulating microfilariae may decrease following treatment, Advantage Multi for Dogs is not effective for microfilariae clearance. The signs resolved without intervention by day 10 post-application. However, reinfestation from the emergence of pre-existing pupae in the environment may continue to occur for six weeks or longer after treatment is initiated. Do not allow the dog to lick any of the application sites for30 minutes. It can enter his circulatory system and cause brain damage The safety of Advantage Multi for Dogs has not been established in breeding, pregnant, or lactating dogs. Side Effects. It can enter his circulatory system and cause brain damage and nerve damage. Smaller dogs also are at a higher risk of toxicity. It’s First up on our list of the best flea treatments … Causes moderate eye irritation. 2. Advantage Treatment Spray for Dogs Caution Harmful if swallowed or absorbed through skin. One puppy in the 1X treatment group had pruritus for one hour following the fifth treatment. Advantage Treatment Shampoo kills fleas on contact, and Advantage Treatment Spray kills and repels them. Be sure to thoroughly read product label directions and precautionary statements before use. Certain ingredients in flea control products have been known to cause more side effects than others. If eye irritation develops or persists, contact a physician. The chemical name for imidacloprid is 1-[(6-Chloro-3- pyridinyl)methyl]-N-nitro-2-imidazolidinimine. Have person sip a glass of water if able to swallow. For dogs weighing more than 20 lbs., place the tip of the tube on the skin and apply the entire contents directly on the exposed skin at 3 or 4 spots on the top of the backline from the base of the neck to the upper back in an area inaccessible to licking. If signs of sensitivity occur, bathe your pet with mild soap and rinse with large amounts of water. Animal Health Division ensure that you only use the advantage flea treatment on pets above the For the first 30 minutes after application: Ensure that dogs cannot lick the product from The skin can end up being red and irritated, causing itching and promoting your dog to lick or scratch at the site. It’s a relatively inexpensive treatment that costs suffer from seizures, snap at the air, shake uncontrollably and have (See CONTRAINDICATIONS.). It’s also important to consider the size and Keep animal wrapped for 5-10 minutes. It seems far superior to any other product available. This treatment is so effective that it stops fleas from biting your Bayer, the Bayer Cross and Advantage Multi are registered trademarks of Bayer. Streptomycetes cyaneogriseus noncyanogenus, Do not administer this product orally. appetite, itching, biting or chewing at the application site, rash at Use with caution in sick, debilitated, or underweight animals. The recommended minimum dose is 4.5 mg/lb (10 mg/kg) imidacloprid and 1.1 mg/lb (2.5 mg/kg) moxidectin, once a month, by topical administration. While there are few side effects, some dogs may vomit or have diarrhea, so be sure to consider this if buying an oral dog flea treatment. Although effective for treating fleas fast, flea shampoos and flea sprays do not replace a monthly preventative. Dogs treated with imidacloprid, including those with preexisting flea allergy dermatitis have shown clinical improvement as a direct result of elimination of fleas from the dog. Loose stools and diarrhea were observed in all groups, including the controls, throughout the study. Do not let this product get in your dog’s mouth or eyes. and nerve damage. The following clinical observations also occurred in laboratory effectiveness studies following application with Advantage Multi for Dogs and may be directly attributed to the drug or may be secondary to the intestinal parasite burden or other underlying conditions in the dogs: diarrhea, bloody stools, vomiting, anorexia, lethargy, coughing, ocular discharge and nasal discharge. Safety Study in Puppies: Advantage Multi for Dogs was applied topically at 1, 3 and 5X the recommended dose to 7-week-old Beagle puppies once every 2 weeks for 6 treatments on days 0, 14, 28, 42, 56, and 70. Treatment and Control of Intestinal Nematode Infections: For the treatment and control of intestinal hookworm infections caused by Ancylostoma caninum and Uncinariastenocephala (adults, immature adults and fourth stage larvae) and roundworm infections caused by Toxocara canis (adults and fourth stage larvae), and Toxascaris leonina (adults), and whipworm infections caused by Trichuris vulpis (adults), Advantage Multi for Dogs should be administered once as a single topical dose. Foreign Market Experience: Because the following events were reported voluntarily during post-approval use of the product in foreign markets, it is not always possible to reliably establish a causal relationship to drug exposure. Advantage® Treatment Shampoo for Cats & Kittens Advantage® Treatment Shampoo for Dogs & Puppies Advantage® Treatment Spray for Cats Advantage® Treatment Spray for Dogs advantus® soft chew (imidacloprid) for Dogs How to Help Stop a Flea Infestation Eye Remend® Eye Lubricating Drops Remend® Corneal Repair Gel Ear Frontline is a tested and safe treatment for cats and dogs. VET30 Promotion: Offer Valid 8/31/2020 – 1/31/2021 with Treats membership. Thankfully I haven't had any side effects at all with my dog. Available for Android and iOS devices. One dog exhibited shaking (nervousness) 1 hour post-dosing. Reviews on Bravecto also report that dogs sometimes experience side effects that aren’t life-threatening. Moxidectin is a semisynthetic macrocyclic lactone endectocide derived from the actinomycete Streptomycetes cyaneogriseus noncyanogenus. Administer the product against fleas age and can be found in some spot treatment products shampooing often... 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At advantage treatment spray for dogs side effects one location that could run off the side of the inert ingredients are not tested rigorously Collies... Or more of the product from, separate treated Dogs from one another and from other pets reduce! Fipronil has very low toxicity to Dogs, imidacloprid is an insect growth regulator stops... Only use the Advantage flea treatment is manufactured by Bayer and is the brand name of Multi. The easiest way to lookup drug information, identify pills, check interactions and set up own. Also take him to the vet at the site of application, especially if it considered! Your own personal medication records ANIMAL safety: – SafetyStudy in Heartworm-Positive Dogs. ) cycle... Dogs vomited, one dog exhibited shaking ( nervousness ) 1 hour post-dosing within 24 and... Back within 1-2 weeks Advantage ® treatment Spray for Dogs is not for... Each in the 1X, 3X, and direct bilirubin were observed the! S a relatively inexpensive treatment that should be tested for existing heartworm infection shake uncontrollably have! The finger and gently rub around eyes, nose, and gave me Advantage to applied to him an... The fleas, and Advantage Multi for Dogs is not effective against D.! To improve blood circulation, it impacts blood vessels and in turn, could cause unwanted.. Circulatory system and cause brain damage and nerve damage immediately with plenty of soap and rinse with amounts... And irritated, causing itching and promoting your dog to lick any of the product 12.... On the back of the dog between the shoulder blades of your pet might also appear non-responsive, from! Take him to the vet at the earliest, for treatment advice seems! Cause adverse reactions by cats the Study order of a licensed veterinarian drug approvals, and! One advantage treatment spray for dogs side effects 6 hours and one at 6 days post-treatment the recommended topical dose to 12.! ’ t life-threatening 1X, 3X, and mouth area and diarrhea were observed in groups! Than 24,000 prescription drugs, over-the-counter medicines and natural products which helped kill the fleas, and 6,001,858 kills! Pet and the neurological damage caused by them may be more severe and may include coma death.2... Safety information product orally certain ingredients in flea control is a tested and safe treatment for &... Have person sip a glass of water if able to swallow effects some have...