Since … Usually it's thought to be caused by raised levels of certain chemicals in the blood, such as hormones. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. To understand what obstetric cholestasis is, you first need to understand a little bit about how the liver works normally. COVID-19: how to treat coronavirus at home. Fax +44 20 7723 0575, Royal College of Obstetricians and Gynaecologists, Obstetric Cholestasis (Green-top Guideline No. But, more worrisome are the potential complications for you and your baby. The evidence is still not clear and further research is being done. If you go to your midwife or doctor with symptoms of ICP/OC you should have blood tests to check if you have the condition. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. For example, in Chile, 2.4% of all pregnancies are affected, with a 5% prevalence in women of Araucanian–Indian origin. UK The risk appears to have gone down in recent years but it isn't known if this is because of better pregnancy care or as a result of obstetricians advising women to have their labour induced at around 37-38 weeks. You might also have liver function tests to make sure there are no other causes of liver problems, such as hepatitis. Research is currently looking at the safety of a medicine called ursodeoxycholic acid. You don't get a skin rash but you may get marks on your skin from where you have scratched. The risk of a stillbirth in a normal pregnancy is about 1 in 200. Order blood tests to check how well your liver is working and measure the level of bile salts in your blood Sometimes it can develop earlier in pregnancy. Sometimes the test is done again at around six weeks after the birth, shortly before your postnatal check, if the levels hadn't completely gone back to normal with the first test. Obstetric cholestasis > Excoriations (scratch marks) may be seen but there are no other typical features > If a rash is present, consider other diagnoses e.g. It is also more common if you are carrying twins, triplets, or more babies. For reasons unknown, ICP is much more common in South America, particularly the country of Chile, where it is 10 times more frequent. Registered in England and Wales. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Anyway I have to go for a blood test tomorrow to check for Obstetric cholestasis - has anyone had this test? Later, as your bump grows, the skin of your tummy (abdomen) is stretched and this may also feel itchy. It only affects pregnant women. See the separate leaflet called Premature Labour for more details. The bile flows down these ducts into larger and larger ducts, eventually leading to the common bile duct. Obstetric Cholestasis or Intrahepatic Cholestasis of Pregnancy (ICP) Until very recently, little was known about obstetric cholestasis or intrahepatic cholestasis of pregnancy (ICP). It is more common if you are from certain ethnic groups, such as South Asians and Araucanian Indians. Bile is a greenish-yellow fluid which contains bile acids, bile pigments and waste products such as bilirubin. A rash is not a symptom of cholestatic jaundice. Obstetric cholestasis is a rare condition. Intrahepatic cholestasis of pregnancy (ICP) is a long, rather complicated name, for a problem that affects about 1% of pregnant women in the United States. 'Cholestasis' means there is a slowing down of the flow of bile down the bile ducts in the liver. Pruritus, elevated liver enzymes and raised serum bile acids are key to the diagnosis of ICP. Liver cells pass bile into bile ducts inside the liver. 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